Soft X-ray Spectromicroscopy of Protein Interactions with Phase-Segregated Polymer Surfaces
Bibliographic record
Abstract
Quantitative spectro-microscopic characterization of the interfaces between polymers and relevant proteins helps understand fundamental issues of protein – polymer interactions and can provide insights into biocompatibility. Synchrotron based X-ray photoemission electron microscopy (X-PEEM) and scanning transmission X-ray microscopy (STXM) are being used to study distributions of proteins adsorbed on chemically heterogeneous polymer surfaces with ~30 nm spatial resolution. The relevant contrast in each technique is X-ray absorption spectroscopy which provides speciation and quantitation of both adsorbed proteins or peptides (and in combinations), simultaneously with chemically sensitive imaging of the underlying polymer substrate. An overview of recent progress in this field is given, along with some comparisons to complementary techniques (AFM and TOF-SIMS) for investigating protein-polymer interfaces.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".