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Record W2511072871 · doi:10.1021/acs.organomet.5b00397

Reactivity of an Unsaturated Iridium(III) Phosphoramidate Complex, [Cp*Ir{κ<sup>2</sup>-<i>N</i>,<i>O</i>}][BAr<sup>F</sup><sub>4</sub>]

2015· article· en· W2511072871 on OpenAlexafffund
Marcus W. Drover, Heather C. Johnson, Laurel L. Schafer, Jennifer A. Love, Andrew S. Weller

Bibliographic record

VenueOrganometallics · 2015
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsUniversity of British Columbia
FundersEngineering and Physical Sciences Research CouncilNatural Sciences and Engineering Research Council of CanadaCanada Research Chairs
KeywordsChemistryPhosphoramidateMedicinal chemistryLigand (biochemistry)BoraneReactivity (psychology)AdductStereochemistryFrustrated Lewis pairHydrideLewis acids and basesCatalysisOrganic chemistryHydrogen

Abstract

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The three-legged piano stool complex [Cp*Ir(κ 2 - N, O -Xyl( N )P( O )(OEt) 2 )(Cl)], [ 1 ] (Cp* = η 5 -C 5 Me 5, Xyl = 2,6-dimethylphenyl), was prepared from reaction of 0.5 equiv of [Cp*IrCl 2 ] 2 with the sodiated phosphoramidate ligand Na[Xyl(N)P(O)(OEt) 2 ]. Treatment of [ 1 ] with Na[BAr F 4 ], [BAr F 4 ] = [B(C 6 H 3 (CF 3 ) 2 ) 4 ], led to the formation of the 16-electron two-legged piano stool species [Cp*Ir(κ 2 - N, O -Xyl( N )P( O )(OEt) 2 )][BAr F 4 ], [ 2 ][BAr F 4 ], which was characterized in both solution and solid state. Reactivity screening revealed that complex [ 2 ][BAr F 4 ] undergoes addition of a variety of Lewis bases to afford the corresponding 18-electron adducts with concomitant movement of the phosphoramidate ligand from κ 2 - N, O to κ 1 - N, [Cp*Ir(κ 1 - N -Xyl( N )P(O)(OEt) 2 )(L) 2 ][BAr F 4 ]; L = CN t Bu, [ 3 ][BAr F 4 ], CNXyl, [ 4 ][BAr F 4 ], MeCN, [ 7 ][BAr F 4 ], bipy, [ 8 ][BAr F 4 ]; bipy = 2,2′-bipyridine. For complex [ 7 ][BAr F 4 ], variable-temperature 31 P{ 1 H} NMR spectroscopy revealed that MeCN coordination was reversible between 238 and 190 K. To probe E–H (E = Si, B) bond activation, complex [ 2 ][BAr F 4 ] was treated with H 2 SiPh 2, providing the five-membered iridacycle [Cp*Ir(κ 2 - N,Si -Xyl( N )P(O Si Ph 2 )(OEt) 2 )][BAr F 4 ], [ 9 ][BAr F 4 ], via geminal Si–H activation, while use of mesityl borane, H 2 BMes (Mes = 2,4,6-trimethylphenyl), afforded the six-membered phosphoramidate-stabilized borane complex [Cp*Ir(κ 3 - N,H,H -Xyl( N )P(OB H 2 Mes)(OEt) 2 )][BAr F 4 ], [ 10 ][BAr F 4 ]. Complexes [ 3 ][BAr F 4 ] and [ 9 ][BAr F 4 ] were additionally characterized by single-crystal X-ray diffraction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.235
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations27
Published2015
Admission routes2
Has abstractyes

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