A Case of Cronkhite-Canada Syndrome Treated by <i>Helicobacter pylori</i> Eradication
Bibliographic record
Abstract
A 53-year-old woman presented alopecia, nail changes and nonbloody diarrhea in April 1998. When the patient visited our medical center in June, alopecia had been improved. Upper gastrointestinal endoscopy demonstrated multiple gastric polyps in the whole stomach and colonoscopy revealed polyposis from the cecum to rectum. Histologic examination of biopsy specimens from the polyps in the stomach and colon revealed hyperplastic changes of the gland, edema and inflammatory infiltration of neutrophiles, eosinocytes, etc. in the interstitium. On the basis of these findings, the patient was diagnosed as Cronkhite-Canada syndrome, but was not treated with steroids or antiplasmins because of improvement of alopecia and nail changes. Helicobacter pylori was found by culture and histological examination. The patient was treated with one week course of omeprazole, amoxicillin and clarithromycin. One year later, Helicobacter pylori was eradicated, and polyposis of the gastrointestinal tract almost disappeared. The patient has no recurrence of alopecia or nail changes.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.004 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.004 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".