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High-throughput discovery of novel developmental phenotypes

2016· article· en· 1,294 citations· W2518901523 on OpenAlex· 10.1038/nature19356

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.004
GPT teacher head0.245
Teacher spread
0.240 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Cell Image Analysis Techniques
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Hospital for Sick ChildrenToronto Centre for PhenogenomicsMount Sinai Hospital
Funders
National Institute of Diabetes and Digestive and Kidney DiseasesNational Cancer InstituteNational Eye InstituteMedical Research CouncilCentre National de la Recherche ScientifiqueBundesministerium für Bildung und ForschungUniversité de StrasbourgInstitut National de la Santé et de la Recherche MédicaleNational Human Genome Research InstituteWellcome TrustAgence Nationale de la RechercheGenome CanadaNational Institutes of HealthOntario GenomicsCancer Research UKPHENOMINGovernment of CanadaINFRAFRONTIER
Keywords
Gene knockoutBiologyPhenotypeGeneticsGeneGene targetingPenetranceComputational biologyKnockout mouseGenetic screenCandidate geneLethal allele
Has abstract in OpenAlex
no