Ion Conducting Nanopores for (Bio)molecular Sensing: the iNAPO Project
Bibliographic record
Abstract
Single conical nanopores in polymer foils are fabricated by means of the ion track etching technique.They are chemically modified so that they selectively react with certain molecules to be analyzed.This specific reaction is electrochemically monitored by measuring the electrolyte current flowing through the nanopores in an electrochemical cell.This current is dependent on the presence and concentration of the molecule to be analysed.Thus, a both sensitive and selective molecular sensor is available.The paper describes the fabrication of the nanopores and their use as sensors.As an example, the sensing of hydrogen peroxide is shown.The polymer nanopores are the base of the project iNAPO.Its goal is the combination of the polymer-based nanopores with biological protein-based nanopores and their implementation into a micro-device in order to create a new type of sensing tool for analytical or medical applications, e.g.such as environmental water analysis and diagnostics of diseases.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".