Self-Assembled Hyaluronic Acid-Gelatin Microhydrogel for Regenerating Neurite-Like Cells from Induced Pluripotent Stem Cells
Bibliographic record
Abstract
Neuronal differentiation of induced pluripotent stem cells (iPSCs) in repeating particulate units of microhydrogel with hybrid hyaluronic acid (HA) and gelatin (Gel) was investigated.HA and Gel were photocrosslinked, assembled, and further used to regenerate neurons from iPSCs.Stained fluorescent images evidenced that the self-assembled microhydrogel comprising 50% HA and 50% Gel was able to preserved phenotypic iPSCs, leading to an improved production of neuronal lineage after induction with nerve growth factor.The current self-assembled HA-Gel microhydrogel constructs can be properly self-assembled for engineered biomaterials in the duplication of nervous tissue from iPS cells after incubation with neurite-inductive factor.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".