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Record W2529094011 · doi:10.4172/2368-0512.1000026

Changes in the extracellular matrix during myocardial remodelling

2016· article· en· W2529094011 on OpenAlexvenueno aff
Markéta Hegarová, Ivan Málek

Bibliographic record

VenueCurrent research. Cardiology · 2016
Typearticle
Languageen
FieldMedicine
TopicCardiac Fibrosis and Remodeling
Canadian institutionsnot available
Fundersnot available
KeywordsExtracellular matrixExtracellularCardiologyMatrix (chemical analysis)ChemistryInternal medicineMedicineBiochemistryChromatography

Abstract

fetched live from OpenAlex

represents the target structure, at the same time, individual ECM components participate to various degrees directly in myocardial remodelling as modulators of a number of signalling pathways. Matricellular proteins are expressed in reaction to pathological stimuli. These have no structural function but modulate interactions between ECM components, nonmyocyte cells and cardiomyocytes. The principal consequence of ECM remodelling is an increase in the fibrous tissue content of the heart. Pharmacological intervention affecting the process of ECM remodelling could improve the prognosis of patients with CHF.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.739
Threshold uncertainty score0.384

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.110
GPT teacher head0.393
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2016
Admission routes1
Has abstractyes

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