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Record W2530901491

Periodontitis as a complication of elevated blood glucose level and it’s management

2015· article· en· W2530901491 on OpenAlex
S. Harinder, Hu

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Diabetes & Metabolism · 2015
Typearticle
Languageen
FieldDentistry
TopicOral microbiology and periodontitis research
Canadian institutionsWestern University
Fundersnot available
KeywordsMedicineBlood sugarPeriodontitisDiabetes mellitusImmune systemInternal medicineInflammationType 2 Diabetes MellitusReceptorComplicationObesityDiseaseImmunologyEndocrinologyPhysiology
DOInot available

Abstract

fetched live from OpenAlex

P is a chronic inflammatory disease of the surrounding structures of teeth. Elevated blood glucose level has a profound effect on progression of periodontitis and results in advance bone loss, deep periodontal pockets and premature loss of teeth. On the other hand, moderate to severe periodontal disease elevates blood sugar levels in the body; increasing the amount of time the body has to function with high blood sugar levels. Sustained high blood glucose levels results in non-enzymatic conjugation of proteins and lipids forming Advanced Glycated End products (AGE ). Receptors of AGE have been identified on cells involved in immune response to bacterial challenges. Binding of AGE to receptors on monocytes, PMNs and macrophages result in production of high levels of inflammatory mediators. Obesity and family history of type II diabetes are risk factors for development of high blood sugar level especially in females. This presentation will describe clinical and radiographic findings in periodontal patients affected by high blood sugar level. Management of these cases will be discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.550
Threshold uncertainty score0.498

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.305
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it