Gelatin‐Based Biomaterials For Tissue Engineering And Stem Cell Bioengineering
Bibliographic record
Abstract
Gelatin is a biocompatible, biodegradable and fully absorbable biopolymer. These properties have attracted significant interests in the use of gelatin for a wide range of tissue engineering applications. This chapter covers the studies that focused on using gelatin-based biomaterials for cardiovascular, bone, hepatic, skin and corneal tissue engineering. It discusses the application of gelatin for wound healing and injectable fillers. Stem cells hold great a potential in tissue regeneration applications due to their self renewal capacity and differentiation toward specialized cell types. The chapter discusses various strategies that have been utilized to modulate stem cell behavior by altering the biochemical and biophysical properties of gelatin. Gelatin-based delivery systems have found success in gene and siRNA delivery, to induce the expression of therapeutic proteins or trigger gene silencing, respectively. Overall, gelatin based drug delivery systems have demonstrated great utility and versatility in many biomedical applications.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.011 | 0.005 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".