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Record W2535221998

Other Rare Polyposis Syndromes

2009· article· en· W2535221998 on OpenAlexaboutno aff
Gabriele Riegler, Annalisa de Leone, Ilaria Esposito

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicGenetic factors in colorectal cancer
Canadian institutionsnot available
Fundersnot available
KeywordsPeutz–Jeghers syndromeCowden syndromeMedicineFamilial adenomatous polyposisAdenomatous polyposis coliGastrointestinal tractMalignancyGastroenterologyDermatologyInternal medicinePathologyColorectal cancerCancerGermline mutationMutationGeneticsBiologyGene
DOInot available

Abstract

fetched live from OpenAlex

The rare gastrointestinal polyposis syndromes are a group of disorders characterized by the presence of multiple polyps in the gastrointestinal tract, associa- ted in some cases with extraintestinal manifestations. These syndromes can be inherited or non-inherited. The first group includes, on the basis of polyp histopathology, adenomatous polyposis (familial adenomatous polyposis (FAP) vari- ants like Gardner's syndrome and Turcot's syndrome) and hamartomatous polyposis (Juvenile Polyposis syndrome, Peutz-Jeghers syndrome, Cowden's disease, and Bannayan-Ryley-Ruvalcaba syndrome), while the second group includes Cronkhite-Canada syndrome and Hyperplastic polyposis. The molecular genetics have not been well defined for all the syndromes. However, these conditions present variable risk of gastrointestinal and extraintestinal invasive malignancy. Therefore management and surveillance programs are different for each syndrome.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.032

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0100.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.292
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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