Regulatory barriers to international scientific innovation: approving new biotechnology in North America
Bibliographic record
Abstract
The regulation of science often differs among countries and leads to a divergence that can create barriers to research, knowledge transfer and product trade. Many types of scientific research are mobile activities that be done in a number of countries for a comparable cost. With technology development firms facing comparable development costs regardless of location, it is well understood that location decisions are driven by the time and monetary costs of compliance with regulatory systems. In this article we show the compatibility of a country's regulatory system with foreign regulatory systems can also impact the viability of research investment. We argue there may be considerable economic gain from bilateral, and eventually multinational, agreements to adopt a harmonized or shared regulatory process. This is particularly germane for the United States and Canada which are already in a free trade agreement.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.011 | 0.025 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.007 | 0.006 |
| Scholarly communication | 0.010 | 0.004 |
| Open science | 0.001 | 0.004 |
| Research integrity | 0.004 | 0.004 |
| Insufficient payload (model declined to judge) | 0.005 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".