MétaCan
Menu
Back to cohort
Record W2549994380 · doi:10.1016/j.dib.2016.11.036

A dataset of multiresolution functional brain parcellations in an elderly population with no or mild cognitive impairment

2016· article· en· W2549994380 on OpenAlexafffund
Angela Tam, Christian Dansereau, AmanPreet Badhwar, Pierre Orban, Sylvie Belleville, Howard Chertkow, Alain Dagher, Alexandru Hanganu, Oury Monchi, Pedro Rosa‐Neto, Amir Shmuel, John C.S. Breitner, Pierre Bellec

Bibliographic record

VenueData in Brief · 2016
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsHotchkiss Brain InstituteOntario Brain InstituteDouglas Mental Health University InstituteMcGill UniversityUniversity of CalgaryUniversité de MontréalInstitut Universitaire de Gériatrie de Montréal
FundersNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchGenentechNational Institutes of HealthServierH. Lundbeck A/SIndustry CanadaU.S. Department of DefenseEli Lilly and CompanyCompute CanadaNorthern California Institute for Research and EducationRocheMcGill UniversityNatural Sciences and Engineering Research Council of CanadaPfizerBioClinicaBiogenNovartis Pharmaceuticals CorporationBristol-Myers Squibb FoundationAlzheimer SocietyF. Hoffmann-La RocheMerckAlzheimer's Drug Discovery FoundationNational Institute on AgingFonds Québécois de la Recherche sur la Nature et les TechnologiesTakeda Pharmaceutical CompanyAbbVieFujirebio EuropeAlzheimer's AssociationGE HealthcareAlzheimer's Disease Neuroimaging InitiativeJohnson and JohnsonMeso Scale Diagnostics
KeywordsCognitive impairmentResting state fMRIPrefrontal cortexFunctional magnetic resonance imagingPopulationCognitionCortex (anatomy)Ventral striatumTemporal lobeBrain mappingStriatumFrontal lobeNeuroscienceComputer sciencePsychologyMedicine

Abstract

fetched live from OpenAlex

We present group eight resolutions of brain parcellations for clusters generated from resting-state functional magnetic resonance images for 99 cognitively normal elderly persons and 129 patients with mild cognitive impairment, pooled from four independent datasets. This dataset was generated as part of the following study: Common Effects of Amnestic Mild Cognitive Impairment on Resting-State Connectivity Across Four Independent Studies (Tam et al., 2015) [1]. The brain parcellations have been registered to both symmetric and asymmetric MNI brain templates and generated using a method called bootstrap analysis of stable clusters (BASC) (Bellec et al., 2010) [2]. We present two variants of these parcellations. One variant contains bihemisphereic parcels (4, 6, 12, 22, 33, 65, 111, and 208 total parcels across eight resolutions). The second variant contains spatially connected regions of interest (ROIs) that span only one hemisphere (10, 17, 30, 51, 77, 199, and 322 total ROIs across eight resolutions). We also present maps illustrating functional connectivity differences between patients and controls for four regions of interest (striatum, dorsal prefrontal cortex, middle temporal lobe, and medial frontal cortex). The brain parcels and associated statistical maps have been publicly released as 3D volumes, available in .mnc and .nii file formats on figshare and on Neurovault. Finally, the code used to generate this dataset is available on Github.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.162
Threshold uncertainty score0.588

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.111
GPT teacher head0.329
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2016
Admission routes2
Has abstractyes

Explore more

Same venueData in BriefSame topicFunctional Brain Connectivity StudiesFrench-language works237,207