Temporal Changes in the Hindgut Health Markers of Labrador Dogs in Response to a Canine-origin Probiotic Lactobacillus johnsonii
Bibliographic record
Abstract
To study the temporal changes in the hindgut health markers in response to a canine-origin probiotic Lactobacillus johnsonii, 15 Labrador adult female dogs were distributed into three equal groups. Dogs in control group (CON) received a placebo MRS broth in the homemade basal diet as per the NRC recommendations. In other two groups, dogs received either canine-origin probiotic (Lactobacillus johnsonii isolated from dog faeces) developed at our laboratory (cPRO) or dairy-origin probiotic (Lactobacillus acidophilus NCDC-15; dPRO) in the same basal diet The experimental duration of 13-weeks in which feeding of probiotics discontinue after 9-weeks, had experimental protocol involving 3-d digestion trial following 0, 30, 60, 75 and 90 d of feeding to ascertain physical, biochemical and microbial assessment of faecal markers. The digestibility of DM remained similar (P>0.05) irrespective of dietary treatments. Faecal biochemical attributes including pH, lactate and ammonia implied positive influence of probiotic supplementation and the positive influence were more evident in canine-origin probiotic supplemented group. Faecal acetate was higher (P<0.05) in dogs of cPRO group as compared to CON, however intermediate values were recorded in dPRO group. Faecal propionate remained unaffected (P>0.05) among all the groups. There was significant (P<0.01) increase in faecal butyrate in both the probiotics fed groups as compared to CON. The faecal concentrations of total VFAs and SCFAs in fresh faeces were higher (P<0.05) in cPRO compared to other two groups. Faecal count of health-positive and healthnegative bacteria revealed that lactobacillus count exhibited higher (P<0.05) values in cPRO, intermediate in dPRO and lower value in CON, with the bifidobacteria population showing highest (P<0.05) value in the both the probiotics supplemented animals. There was a reducing effect in the health-negative clostridia and coliforms in cPRO and dPRO compared to CON. Overall, the results concluded that Probiotic supplementation was effective in improving the hind gut health, antioxidant and metabolic response in dogs. However, the present results are indicative of the superiority of canine-origin probiotic (cPRO) over the dairy-origin (dPRO) one, so far as its application for canines is concerned.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".