In vivo antidiarrheal activity evaluation of the seeds of Sorghum bicolor L. (Poaceae)
Bibliographic record
Abstract
The seeds of Sorghum bicolor (Family: Poaceae) have been used traditionally for treatment of diarrhea but its efficacy needs to be evaluated. This study was carried out to evaluate the in vivo antidiarrheal activity of 80% methanol crude extract of the seeds of locally grown S.bicolor. This screening was conducted at 100mg/kg, 200mg/kg and 400mg/kg extract doses by using three standard methods of bioassay: castor oil-induced diarrhea, castor oil-induced enteropooling and castor oil-induced gastrointestinal transit tests. Depending on the model, data on the onset of defecation, number of wet feces, total number of feces, weight of intestinal fluid as well as length of intestinal transit were collected. In addition, preliminary phytochemical and acute toxicity studies were conducted. The presence of phenols, flavonoids, tannins, terpenoids and sterols in the extract was confirmed. On the other hand, the oral median lethal dose (LD50) of the extract was estimated to be higher than 2000mg/kg. The 200mg/kg and 400mg/kg extract doses especially demonstrated a very significant (P
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".