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Iodine: Biochemistry, Deficiency and Application in Clinical Nutrition

2016· article· en· W2561012436 on OpenAlexvenueno aff
Helena Jenzer

Bibliographic record

VenueCanadian Journal of Clinical Nutrition · 2016
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicDrug-Induced Hepatotoxicity and Protection
Canadian institutionsnot available
Fundersnot available
KeywordsIodineIodine deficiencyIodised saltThyroidChemistryBasal metabolic rateAqueous solutionSolventSalt (chemistry)BiochemistryEndocrinologyInternal medicineMedicineOrganic chemistry

Abstract

fetched live from OpenAlex

Iodine is an essential trace element needed for normal metabolic functions. Although 70% of the body’s iodine is distributed in other tissues, the thyroid gland is the most relevant organ susceptible to iodine effect. In aqueous solution, due to the ability of keeping several oxidation states, the species I-, I2, OI-, HOI, IO3 -, H5IO6, and H3IO6 2- are likely to co-exist. Their steady state and reaction equilibrium depend on pH, temperature and solvent conditions. Suitable food sources rich in iodine are plants from iodine-rich soil, iodized salt, or seafood. The principal objectives of nutritional supply with iodine are to cover the needed daily intake and to stabilize basal metabolic rate. Keywords: Iodine Deficiency, Clinical Nutrition, Biochemistry, Stereochemistry

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.028
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.166
GPT teacher head0.483
Teacher spread0.317 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2016
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Clinical NutritionSame topicDrug-Induced Hepatotoxicity and ProtectionFrench-language works237,207