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Record W2562877916 · doi:10.1107/s2414314616019775

2,3,5,6-Tetrakis{[(pyridin-2-yl)sulfanyl]methyl}pyrazine

2016· article· en· W2562877916 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueIUCrData · 2016
Typearticle
Languageen
FieldChemistry
TopicSynthesis and Characterization of Heterocyclic Compounds
Canadian institutionsCanAm Bioresearch (Canada)
FundersSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungNational Science Foundation
KeywordsPyrazineChemistryMoleculeSulfanylRing (chemistry)CrystallographyCrystal structurePyridineStereochemistryPoint reflectionMedicinal chemistryOrganic chemistry

Abstract

fetched live from OpenAlex

The title compound, C 28 H 24 N 6 S 4 , synthesized by the reaction of 2,3,5,6-tetrakis(bromomethyl)pyrazine with 2-mercaptopyridine, crystallizes with one half-molecule in the asymmetric unit. The whole molecule is generated by inversion symmetry, the centre of the pyrazine ring being located about an inversion centre. The pyridine rings of the unique (pyridin-2-ylsulfanyl)methyl substituents are inclined to the pyrazine ring by 38.7 (3) and 75.6 (2)°, and by 66.0 (3)° to one another. In the crystal, molecules are linked via C—H...π interactions, forming chains along the b -axis direction. The chains are linked by offset π–π interactions [intercentroid distance = 3.682 (3) Å], forming layers lying parallel to the bc plane.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.570
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0170.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.233
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it