ARMS-PCR based diagnosis of APCB and KRAS genes in colorectal cancer patients in Iraqi Sulaimania province
Bibliographic record
Abstract
Amplification Refractory Mutation System (ARMS) assay is achieved for 30 blood samples of colorectal cancer (CRC) patients including 17 male and 13 female in order to determine the mutations in APCB gene and a proto-oncogene KRAS. ARMS-PCR analysis shows that all 30 samples are negative for I1307K variant (APCB) and seven common mutations in codons 12 and 13 (APCB). In addition two CRC patient samples are randomly chosen and purified for sequencing at Genome Center/KOYA University, then the sequence of the samples were BLAST on NCBI Website. The sequence alignment showed that both samples were wild for I1307K (APCB) and (G12S, G12C, G12A, G12D, G12V, G13D) (KRAS). We believe that these variants might absent in CRC patients of Iraqi Sulaimania province.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".