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Record W2564584662 · doi:10.1080/00085030.2017.1258212

An assessment of oral fluid drug screening devices

2016· article· en· W2564584662 on OpenAlexaffvenueabout
D J Beirness, D'Arcy Randall Smith

Bibliographic record

VenueCanadian Society of Forensic Science Journal · 2016
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicForensic Toxicology and Drug Analysis
Canadian institutionsRoyal Canadian Mounted PoliceCanadian Centre on Substance Use and Addiction
Fundersnot available
KeywordsDrugMedicineCannabisDrug detectionPharmacologyAmphetamineInternal medicinePsychiatryChromatographyChemistry

Abstract

fetched live from OpenAlex

This project was to examine point-of-contact (POC) oral fluid drug screening devices to determine the suitability of such devices for potential use in the enforcement of drug-impaired driving in Canada. Oral fluid samples were collected from a group of individuals who admitted to having recently ingested drugs as well as a number of individuals who had not been using drugs. These samples were tested on one of three oral fluid screening devices to determine the presence of cannabis, cocaine, amphetamine, methamphetamine, opioids, and benzodiazepines. Each participant also provided a second oral fluid sample that was sent to a reference laboratory for independent analysis. Comparison of the results from the oral fluid screening device and those from the laboratory analysis provided estimates of sensitivity and specificity for each of the six drugs/drug categories. Sensitivity exceeded 0.80 for cannabis, cocaine, methamphetamine, and opioids. False positive rates for these drugs/drug categories were all between 3% and 7%. Specificity exceeded 0.90 for all drugs/drug categories. These findings indicate that oral fluid screening could prove to be a valuable tool in the detection of driver drug use in Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.048
Threshold uncertainty score0.095

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.430
Teacher spread0.364 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2016
Admission routes3
Has abstractyes

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