Nutritional intake, depressive symptoms and vitamin D status in hypertensive patients in the north of Iran: A case–control study
Bibliographic record
Abstract
We investigated vitamin D status, body size, nutritional intake and depression status in hypertensive patients in the north of Iran that have special dietary habit and lifestyle according to their culture and geographical situation. This study was conducted on 127 patients with newly recognized hypertension and the 120 normal participants, in the north of Iran. Anthropometric data was measured and demographic characteristics, dietary intake, depression and medical status were collected by valid questionnaires. Blood samples were measured for 25-hydroxyvitamin D. Hypertensive patients had significantly lower serum 25-hydroxyvitamin D than control group (16 ± 8.7 ng/mL vs. 19.8 ± 8.4 ng/mL; P = 0.04). In adjusted model, serum 25-hydroxyvitamin D of less than 30 ng/mL was associated with an almost 4-fold odds of hypertension. The odds of hypertension in depressed patients was 1.2 times higher than in those without depression (p = 0.002). After adjusted logistic regression analysis for energy intake, significant association was observed between hypertension and some dietary nutrients, including cholesterol, fiber and vitamin D intake. There was no significant association between hypertension and body weight, waist circumference as well as BMI. The vitamin D status was lower in the most individuals and it causes a considerable increase in the risk of hypertension. Undesirable intake of some nutrients and depression also increase the risk of developing hypertension. Health training about suitable dietary habits, easier access to vitamin D supplementation and screening for depression in patients with hypertension are cost-effective tools to improve outcomes in Iran. Se investigó el nivel de vitamina D, el tamaño corporal, la ingesta nutricional y el estado depresivo en pacientes hipertensos del Norte de Irán con unos hábitos alimenticios y estilo de vida especiales en función de su cultura y localización geográfica. El presente estudio se llevó a cabo en el Norte de Irán, con 127 pacientes recién diagnosticados de hipertensión y 120 individuos normales. Se midieron datos antropométricos y características demográficas, ingesta nutricional, depresión y estado médico por medio de cuestionarios válidos. Se analizaron los valores sanguíneos de 25-hidroxivitamina D. Los pacientes hipertensos presentaron unos valores significativamente inferiores de 25-hidroxivitamina D que los del grupo de control (16 ± 8,7 ng/ml vs. 19,8 ± 8,4 ng/ml; p = 0,04). En el modelo ajustado los valores de 25-hidroxivitamina D inferiores a 30 ng/ml se asociaron con una probabilidad hasta 4 veces mayor de padecer hipertensión. La probabilidad en los pacientes con depresión fue 1,2 veces más alta que en los pacientes no depresivos (p = 0,002). Después de realizar una regresión logística ajustada y analizar la ingesta energética se apreció una asociación significativa entre la hipertensión y algunos nutrientes alimenticios como el colesterol, la fibra y la ingesta de vitamina D. No existió una asociación significativa entre la hipertensión y el peso corporal, el perímetro de la cintura ni el IMC. Los niveles de vitamina D eran más bajos en la mayoría de individuos, y esto ocasiona un aumento considerable del riesgo de padecer hipertensión. La ingesta inapropiada de algunos nutrientes y la depresión también incrementan el riesgo de hipertensión. La formación sanitaria sobre hábitos alimenticios saludables, un mayor acceso a los suplementos de vitamina D y la detección de la depresión en pacientes hipertensos son herramientas económicamente rentables que mejorarán los resultados en Irán.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".