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Record W2565483775 · doi:10.1093/neuonc/nov225.46

NIMG-46THE USE OF CLINICAL FUNCTIONAL MAGNETIC RESONANCE IMAGING IN BRAIN TUMOUR PATIENTS FOR SURGICAL PLANNING: A SINGLE-SURGEON RETROSPECTIVE COHORT STUDY AT A CANADIAN CENTER

2015· article· en· W2565483775 on OpenAlexaffabout
Jonathan C. Lau, Joseph Megyesi

Bibliographic record

VenueNeuro-Oncology · 2015
Typearticle
Languageen
FieldMedicine
TopicGlioma Diagnosis and Treatment
Canadian institutionsWestern University
Fundersnot available
KeywordsMedicineMagnetic resonance imagingRetrospective cohort studyFunctional magnetic resonance imagingCohortRadiologySingle CenterCraniotomySurgeryInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Advanced imaging techniques such as functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) are being increasingly used for the pre-operative evaluation of patients with brain tumors. METHODS: The study is a retrospective chart review investigating the use of fMRI from 2002-2013 in the pre-operative evaluation of brain tumour patients. Baseline demographic and clinical data were collected. The specific fMRI protocols used for each patient were recorded. RESULTS: 60 patients were identified over the twelve-year period. The type of tumours most commonly investigated were low-grade glioma, glioblastoma multiforme and meningioma. Most common presenting concerns were seizures (46%), change on surveillance (15%), language deficits (11%), and headache (10%). There was a predominance of left-hemispheric lesions investigated with fMRI (77.6% versus 22.4% for right). The most commonly involved lobes were frontal (46.5%), temporal (28.8%), parietal (16.4%), then insular (5.5%). The most common fMRI paradigms were language (85.2%), motor (79.6%), sensory (18.5%), and memory (9.3%). Most patients ultimately underwent a craniotomy (73.2%) while smaller groups underwent stereotactic biopsy (10.7%) and non-surgical management (16.1%). Time from request for fMRI to actual fMRI acquisition was 3.2 +/− 2.3 weeks. Time from fMRI acquisition to intervention was 5.2 +/− 5.4 weeks. CONCLUSIONS: We have characterized patient demographics in a retrospective single-surgeon cohort undergoing pre-operative clinical fMRI at a Canadian center. Our experience suggests an acceptable wait time from scan request to scan completion/analysis and from scan to intervention.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.614
Threshold uncertainty score0.776

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.004
Science and technology studies0.0030.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.344
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes2
Has abstractyes

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