Neurotoxicological Effects of Municipal Effluents in Fathead Minnow Pimephale Promelas
Bibliographic record
Abstract
Municipal effluents are known to be able of disrupting neuro-endocrine signaling pathways in oviparous organisms.The purpose of this study was to examine the neurotoxicity of a chemically-treated municipal effluent to adult fathead minnow (Pimephales promelas) after 21 days.Brain somatic index and lipid peroxidation (LPO), monoamine oxidase (MAO) and acetylcholinesterase (AChE) levels were determined in both male and female fish.The estrogenicity of the municipal effluent was confirmed by measuring vitellogenin production and energy expenses in the liver.Brain MAO and AChE activities increased at low effluent concentrations and decreased at higher concentrations (>10% v/v).The data suggest that males expend more metabolic energy than females and was related to vitellogenin, and that brain activity is impaired in both sexes in the presence of the effluent.In conclusion, exposure to municipal effluents could produce biochemical changes in the central nervous system in fish.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".