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Record W2579776684 · doi:10.1002/slct.201601830

An Unprecedented Synthesis of <i>N</i> ‐Phenyl Amides <i>via</i> Cleavage of Benzotriazole Ring under Free Radical Condition

2017· article· en· W2579776684 on OpenAlex
Anoop Singh, Dhananjay Kumar, Nidhi Mishra, Vinod K. Tiwari

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueChemistrySelect · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicChemical Synthesis and Analysis
Canadian institutionsnot available
FundersCouncil of Scientific and Industrial Research, IndiaCentral Drug Research InstituteCanadian Institute of Steel Construction
KeywordsBenzotriazoleBenzoxazoleChemistryAmideRing (chemistry)Cleavage (geology)Yield (engineering)StereochemistrySingle crystalMedicinal chemistryOrganic chemistryCrystallographyMaterials science

Abstract

fetched live from OpenAlex

Abstract An attempt of Bu 3 SnH mediated cyclization of acylbenzotriazoles (RCOBt) to corresponding benzoxazole failed; instead, corresponding N ‐phenylamides were achieved in good yield. The reactions proceed via reductive cleavage of benzotriazole ring with consequent evolution of molecular nitrogen ( N 2 ). A diverse range of amide has been achieved in high yields. Structures of all the compounds have been elucidated using IR, MS, 1 H and 13 C NMR, while four of them ( 3 o, 3 w, 4 and 5 ) have also been characterized by single crystal X‐ray analysis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.812

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.259
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it