On the inverse problem of detecting cardiac ischemias: theoretical analysis and numerical reconstruction
Bibliographic record
Abstract
In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the electric potential in the myocardial tissue. The goal is the detection of a small inhomogeneity $ω_\varepsilon$ (where the coefficients of the equation are altered) located inside a domain $Ω$ starting from observations of the potential on the boundary $\partial Ω$. Such a problem is related to the detection of myocardial ischemic regions, characterized by severely reduced blood perfusion and consequent lack of electric conductivity. In the first part of the paper we provide an asymptotic formula for electric potential perturbations caused by internal conductivity inhomogeneities of low volume fraction, extending the results published in [7] to the case of three-dimensional, parabolic problems. In the second part we implement a reconstruction procedure based on the topological gradient of a suitable cost functional. Numerical results obtained on an idealized three-dimensional left ventricle geometry for different measurement settings assess the feasibility and robustness of the algorithm.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.010 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.000 | 0.004 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".