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Autoanticuerpos y vasculitis sistémicas

2010· article· en· W2580514327 on OpenAlexaff
Paula Alba, María Laura Bertolaccini, Munther A. Khasmashta

Bibliographic record

VenueRevista de la Facultad de Ciencias Médicas de Córdoba · 2010
Typearticle
Languageen
FieldMedicine
TopicVasculitis and related conditions
Canadian institutionsWomen's Health Research Institute
Fundersnot available
KeywordsVasculitisMedicinePathologyDisease

Abstract

fetched live from OpenAlex

The term vasculitis includes a heterogeneous group of diseases that have in common inflammatory injury of the blood vessels. The evolution of this inflammatory process leads to ischemia or, sometimes, haemorrhage of the organs dependent on these vessels. The location of the affected vessels and tissues will determine the appearance of a wide variety of clinical manifestations and, therefore, a very variable prognosis.The different entities grouped under the term vasculitis include Wegener's granulomatosis, Churg-Strauss syndrome, classical panarteritis nodosa, microscopic polyangeitis, Kawasaki disease and classical leukocyte vasculitis, which predominantly affect small and medium-sized vessels. Giant cell arteritis and Takayasu arteritis mainly affect large vessels. We can find primary vasculitis (without association with another underlying disease) or secondary to both infectious processes and autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.). Neutrophil anticitoplasma antibodies (ANCA) were initially described by Davies et al. (2) in patients with glomerulonephritis. They are directed against enzymes present in the granules.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0090.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.285
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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