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Female-specific effect of the BDNF gene on Alzheimer's disease

2017· article· en· W2580976313 on OpenAlexfundno aff
Guodong Li, Rui Bi, Dengfeng Zhang, Min Xu, Rongcan Luo, Dong Wang, Yiru Fang, Tao Li, Chen Zhang, Yong‐Gang Yao

Bibliographic record

VenueNeurobiology of Aging · 2017
Typearticle
Languageen
FieldNeuroscience
TopicNerve injury and regeneration
Canadian institutionsnot available
FundersNational Institute on AgingJanssen Research and DevelopmentBureau of Frontier Sciences and Education, Chinese Academy of SciencesNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchNational Institutes of HealthServierInnogeneticsElanEisaiAlzheimer's Drug Discovery FoundationChinese Academy of SciencesNorthern California Institute for Research and EducationPfizerBioClinicaIXICOTakeda Pharmaceutical CompanyGenentechBiogen IdecMedpaceNovartis Pharmaceuticals CorporationU.S. Department of DefenseEli Lilly and CompanyBristol-Myers SquibbF. Hoffmann-La RocheSynarcRocheMerckAlzheimer's AssociationGE HealthcareAlzheimer's Disease Neuroimaging InitiativeJohnson and JohnsonMeso Scale Diagnostics
Keywordsrs6265EndophenotypeDiseaseNeurotrophic factorsBrain-derived neurotrophic factorBiomarkerGenetic associationMedicineOncologyAlzheimer's diseaseInternal medicineNeuroscienceBioinformaticsGenePsychologyGenotypeBiologySingle-nucleotide polymorphismGeneticsPsychiatryCognition

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score0.297

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.298
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations51
Published2017
Admission routes1
Has abstractno

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