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Bayesian longitudinal low-rank regression models for imaging genetic data from longitudinal studies

2017· article· en· W2581851498 on OpenAlexfundno aff
Zhaohua Lu, Zakaria Khondker, Joseph G. Ibrahim, Yue Wang, Hongtu Zhu

Bibliographic record

VenueNeuroImage · 2017
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods and Inference
Canadian institutionsnot available
FundersNational Institute of Mental HealthNational Institute on AgingCanadian Institutes of Health ResearchNational Institutes of HealthTakeda Pharmaceutical CompanyIXICONational Institute of General Medical SciencesH. Lundbeck A/SNational Cancer InstituteServierEisaiNorthern California Institute for Research and EducationPfizerBiogenBioClinicaGE HealthcareAlzheimer's Disease Neuroimaging InitiativeMeso Scale DiagnosticsF. Hoffmann-La RocheGenentechCancer Prevention and Research Institute of TexasNovartis Pharmaceuticals CorporationEli Lilly and CompanyBristol-Myers SquibbRocheMerckAlzheimer's Drug Discovery FoundationAbbVieAlzheimer's AssociationNational Science Foundation
KeywordsMarkov chain Monte CarloBayesian probabilityComputer scienceMultivariate statisticsImaging geneticsNeuroimagingArtificial intelligenceRegressionSingle-nucleotide polymorphismRandom effects modelPattern recognition (psychology)Machine learningStatisticsMathematicsBiologyGeneticsMedicineGeneNeuroscience

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.057
metaresearch head score (Gemma)0.177
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.057
Threshold uncertainty score0.304

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0570.177
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0050.004
Bibliometrics0.0040.005
Science and technology studies0.0020.005
Scholarly communication0.0050.006
Open science0.0070.004
Research integrity0.0050.008
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.375
GPT teacher head0.470
Teacher spread0.095 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2017
Admission routes1
Has abstractno

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