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Record W2586859237 · doi:10.1093/ecco-jcc/jjx002.855

P732 Clinical characteristics of inflammatory bowel disease in Belgian immigrants from Moroccan and Caucasian origin

2017· article· en· W2586859237 on OpenAlexaboutno aff
L. de Ville de Goyet, Tom G. Moreels, M.A. Denis, Bénédicte De Vroey, N de Suray, Christina Mouradides, Abdulsalam Y. Taha, C. De Bouvere, Hubert Piessevaux, Olivier Dewit

Bibliographic record

VenueJournal of Crohn s and Colitis · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineUlcerative colitisInflammatory bowel diseaseInternal medicineColectomyDiseaseGastroenterologyCohortMedical prescriptionPopulationRetrospective cohort studyCrohn's diseaseImmigration

Abstract

fetched live from OpenAlex

Background: Moroccans are a growing minority in Belgium since the 1960s. Few studies have examined the characteristics of inflammatory bowel disease (IBD) in this population. The aim of our study was to compare IBD characteristics between immigrants from Moroccan and Caucasian origin. Methods: We performed a retrospective chart review of all first and second generation immigrants with Crohn's disease (CD) or Ulcerative colitis (UC) followed in our IBD Center from 2010 to 2016. Disease characteristics (Montreal classification), clinical variables and treatment were extracted to define disease severity and prognosis. Results: A total of 83 Moroccans (57 CD/26 UC, 53 men) and 72 Caucasian immigrants (42 CD/30 UC, 37 men) patients were analysed. For CD patients, penetrating disease (26/57 vs 11/42), perineal localisation (24/57 vs 12/42) were more frequent in Moroccan. Although there were no significant differences in medication prescription between the two groups (immunosuppressive:IS (49/57 vs 32/42), biologics (32/57 vs 23/42), there was a higher number of hospitalisations (37/57 vs 15/42) and surgeries (33/57 vs 19/42) in the Moroccan population especially with the most severe disease who needed a definitive stoma (5/57 vs 0/42). For UC patients (26 Moroccans, 30 Caucasians), no differences in localisation, medications or need for hospitalisation were observed. Colectomy was performed in 4 Moroccans and 3 Caucasians. Table 1. Summary of results Conclusions: We report a higher proportion of CD in Moroccan compared to Caucasian immigrants in our active IBD cohort. Moreover, Moroccan CD patients tend to have more severe disease, characterized by more penetrating disease, more perineal disease leading to higher rates of CD-related surgery and definitive stoma. Further research is required to confirm these observations and determine if these findings reflect genetic or environmental differences.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.284
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2017
Admission routes1
Has abstractyes

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