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Inorganic Nanoplatforms for Simultaneous Cancer Imaging and Therapy: Status and Challenges

2017· article· en· W2587927574 on OpenAlexvenueno aff
Mian Chen

Bibliographic record

VenueJournal of cancer research updates · 2017
Typearticle
Languageen
FieldEngineering
TopicNanoplatforms for cancer theranostics
Canadian institutionsnot available
Fundersnot available
KeywordsNanomaterialsNanotechnologyCancer therapyNanoparticleMaterials scienceCancer imagingNanomedicineColloidal goldCancerMedicineInternal medicine

Abstract

fetched live from OpenAlex

Functional nanomaterials have inspired revolutionary methods for cancer early diagnosis, treatment, and prevention. For instance, the imaging property of nanomaterials with high resolution and sensitivity can be used for noninvasive detection of cancer and visualization of drug transport. Meanwhile, the therapeutic property of nanomaterials with controllable fashion will increase therapy efficacy and decrease adverse side effect. Thus, compared to traditional treatment approaches, the nanomaterials which combines imaging and therapeutic functionalities, will be more suitable for cancer theranostics. This review introduces several types of inorganic nanoparticles, including silica nanoparticles, upconversion nanoparticles, iron oxide nanoparticles and gold nanoparticles, which can been explored as theranostic nanoplatforms for simultaneous cancer imaging and therapy. We also cover the ongoing challenges of these nanoparticles in clinical applications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.877
Threshold uncertainty score0.584

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.062
GPT teacher head0.361
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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