Bibliographic record
Abstract
Zika virus is a enveloped, non-segmented, ichoshedral single-stranded, negative-sense RNA virus. It belongs to the Flaviviridae and was first isolated in 1947 from a monkey in the Zika forest, Uganda, then in mosquitoes (Aedes africanus) in the same forest in 1948 and in a human in Nigeria in 1952. Before 2007, viral circulation and a few outbreaks were documented in tropical Africa and in some areas in Southeast Asia. In 2015, Zika viral disease outbreaks were reported in Brazil of South America for the first time and it is now considered as an emerging infectious disease. This ongoing outbreak of Zika virus that began in Brazil has spread too much of South and Central America (except Canada and Chile) and the Caribbean. According to the CDC, Brazilian health authorities reported more than 404 cases of microcephaly between October 2015 and January 2016. Seventeen of those cases have a confirmed link to the Zika virus. Its natural reservoir is yet to be unknown. Transmission mainly by mosquito Aedes aegypti but it can be transmitted from human to human by blood transfusion, saliva, urine and sexual contact. Most dangerous transmission is mother to fetus through placenta. Its actual pathogenesis is not clear but the pathogenesis of the virus is hypothesized to start with an infection of dendritic cells near the site of inoculation, followed by a spread to lymph nodes and the bloodstream Other than congenital malformation (microcephaly) disease symptoms are usually mild and short-lasting self-limiting febrile illness of 4-7 days duration without severe complications. No commercial diagnostic method against Zika virus are available. The virus constitutes an important public health threat in America and also worldwide as no effective treatment or vaccine is available till now. The World Health Organization (WHO) has declared the microcephaly condition, linked to the mosquito-borne virus, a global public health emergency.Anwer Khan Modern Medical College Journal Vol. 7, No. 2: Jul 2016, P 29-35
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.002 | 0.003 |
| Insufficient payload (model declined to judge) | 0.013 | 0.004 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".