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Record W2588217862 · doi:10.1093/ndt/gfw175.31

SP589COGNITIVE FUNCTION TESTED BY MULTI-DOMAIN ASSESSMENT IS REDUCED DURING HAEMODIALYSIS

2016· article· en· W2588217862 on OpenAlexaboutno aff
Mark Findlay, Deborah McGlynn, Jesse Dawson, Patrick B. Mark

Bibliographic record

VenueNephrology Dialysis Transplantation · 2016
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineHemodialysisFunction (biology)Renal functionIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

Introduction and Aims: Patients with established renal failure (ERF) receiving dialysis score lower on cognitive functioning testing than the general population. Analogous to myocardial stunning observed during dialysis we performed assessments of cognitive function during and out with haemodialysis to determine the effect dialysis may have on cerebral function. Methods: Patients receiving hospital haemodialysis for ERF in a large tertiary referral centre were recruited. We excluded all those with known cerebrovascular or cognitive disorders. A neurocognitive battery was performed during a routine dialysis session and on a non-dialysis day, allowing a gap of 3-4 weeks, to reduce learning effect. We used a multi-domain assessment consisting of the Montreal Cognitive Assessment (MOCA), Semantic and Phonemic fluency tests, Letter Digit Substitution Test (LDST), Trail Making Test A and B (TMT-A, TMT-B) and the revised Hopkins Verbal Learning Test (HLVT-R). Baseline cognitive function was compared to the 50th percentile population normative values (matched for age, sex and educational level where appropriate) and a Wilcoxon-signed rank test applied to compare scores during and out with dialysis. Data were analysed using SPSS v22.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.373
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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