Free Flap Failure Associated with Heparin-Induced Thrombocytopenia: Is It Preventable?
Bibliographic record
Abstract
Heparin-induced thrombocytopenia (HIT) is a serious adverse effect of unfractionated heparin, particularly in the setting of microsurgery, with a reported salvage rate of <25% of free flaps. HIT presenting as venous thromboembolisms (VTEs) can be a more challenging problem to the reconstructive surgeon. The hematology literature reports a prevalence of HIT as high as 12% among patients presenting with VTEs. Complications associated with HIT are preventable if a high index of suspicion is maintained and proper treatment is implemented. A 68-year-old man with VTEs who failed a parascapular fasciocutaneous flap to the forearm secondary to undiagnosed HIT is reported. The authors propose an algorithm to approach such a dilemma and implement adequate treatment measures before commencing any microsurgical procedures in patients to minimize any untoward consequences.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.010 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".