Tests for epistasis of bimD with UV repair genes representing four epistatic groups and their putative types of DNA repair in Aspergillus nidulans
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Bibliographic record
Abstract
bimD6, a ts mitotic mutant sensitive to UV only in dividing cells and defective in recombination, was tested for epistasis with members of the four Uvs groups of A. nidulans. UV survival of quiescent and germinating conidia was compared. While details varied between tests, results from UV-treated germinating conidia consistently showed additive or synergistic interaction. This suggested a new type of function for bimD and perhaps indirect effects on DNA repair and recombination, in line with recent evidence for defects in chromosome cohesion and compaction in mutants of bimD and its homologs (van Heemst et al. 2001 PNAS 98:6267-6272).
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it