Successful treatment of chronic canine blastomycosis in a Labrador retriever with sterile histopathology
Bibliographic record
Abstract
A four‐year‐old, neutered male Labrador retriever from Minnesota, USA was presented to a dermatology referral clinic for evaluation of waxing and waning paronychia and multifocal cutaneous nodules of five months’ duration. The condition was managed before referral with antibiotics and glucocorticoids resulting in a partial response, but new lesions continued to develop. Skin biopsies made both before and after referral revealed pyogranulomatous dermatitis and fibrosis with negative fungal stains. However, acetate tape impression cytology performed at time of referral detected a single blastomyces organism; thus, a definitive diagnosis of blastomycosis was made. Treatment with fluconazole followed by generic itraconazole resulted in rapid, full recovery in three months’ time. Thoracic radiographs at the time of blastomycosis diagnosis were within normal limits, despite history of mild cough. This case highlights the potential pitfalls in diagnosis and treatment of canine blastomycosis.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".