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Record W2592777041 · doi:10.21037/jtd.2017.02.32

Thymectomy for myasthenia gravis: what’s next?

2017· letter· en· W2592777041 on OpenAlexaff
Marc de Perrot, Laura Donahoe

Bibliographic record

VenueJournal of Thoracic Disease · 2017
Typeletter
Languageen
FieldMedicine
TopicMyasthenia Gravis and Thymoma
Canadian institutionsToronto General HospitalUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsThymectomyMyasthenia gravisMedicineImmunology

Abstract

fetched live from OpenAlex

Thymectomy for myasthenia gravis (MG) has been performed since Alfred Blalock observed in 1936 that a young woman had remission of her myasthenia after a thymectomy for a cystic tumor of the thymus. Over the ensuing 80 years, multiple retrospective series of thymectomy for non-thymomatous MG have been published suggesting the potential benefit of thymectomy in patients with MG. However, the role of thymectomy in non-thymomatous MG remained a topic of controversy due to the absence of a randomized trial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.123
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.367
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2017
Admission routes1
Has abstractyes

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