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Clinical and hematobiochemical response in canine monocytic ehrlichiosis seropositive dogs of Punjab

2017· article· en· W2593531781 on OpenAlexaboutno aff
Manasa R. Kottadamane, P. S. Dhaliwal, Lachhman Das Singla, Baljider Kumar Bansal, Sanjeev Uppal

Bibliographic record

VenueVeterinary World · 2017
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsnot available
FundersGuru Angad Dev Veterinary and Animal Sciences University
KeywordsEhrlichia canisEhrlichiosisVeterinary medicineMedicineSeroprevalenceCanisEhrlichiaInternal medicineImmunologyGastroenterologyAntibodySerologyBiologyTick

Abstract

fetched live from OpenAlex

Aim: As in India especially, the Punjab state sero-prevalence and distribution of ehrlichiosis in relation to clinicohematobiochemical response remains largely unexplored.Thus, this study was designed to determine the prevalence of vector (tick)-borne tropical canine pancytopenia caused by Ehrlichia canis through enzyme labeled ImmunoComb ® (IC) assay in dogs from in and around Ludhiana, Punjab.Correlation of prevalence was made with various clinico-hematobiochemical parameters.Materials and Methods: Seroprevalence study was carried out using IC ® test kit (Biogal, Galed Labs).The study was conducted in 84 dogs presented to the Small Animal Clinics, Teaching Veterinary Clinical Complex, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab.Results: Out of 84 suspected dogs for ehrlichiosis, based on peripheral thin blood smear examination 12 (14.28%)cases were positive for the morulae of E. canis and 73 (86.90%) dogs were found positive to E. canis antibodies through IC ® canine Ehrlichia antibody test kit, respectively.Among the different age groups 1-3 years of aged group showed highest prevalence (41.09%), followed by the 3-6 years age group (32.87%), infection levels were lower in the <1 year of age group dogs (13.69%) and more than 6 years age group dogs (12.32%).The highest prevalence was seen in Labrador retriever.This study indicates that season plays a very important role in the prevalence of ehrlichiosis.The most common findings observed were anemia, leukocytosis, neutropenia, lymphopenia, thrombocytopenia, eosinophilia followed by hyperbilirubinemia, increased levels of aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase, hypoalbuminemia, hyperglobulinaemia, decrease in albumin and globulin ratio, increase in blood urea nitrogen and creatinine.Conclusions: Serological techniques like IC ® are more useful for detecting chronic and subclinical infections and are ideally suited to epidemiological investigations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.335
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations33
Published2017
Admission routes1
Has abstractyes

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