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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.
Full frame distilled prediction
Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
- Candidate categories
- none
- Consensus categories
- none
- Domain
- Candidate signal: noneConsensus signal: none
- Study design
- Candidate signal: Bench or experimentalConsensus signal: none
- Genre
- Candidate signal: EmpiricalConsensus signal: Empirical
- Teacher disagreement score
- 0.068
- Threshold uncertainty score
- 0.474
- Validation status
machine_predicted_unvalidated·codex-gemma-dda1882f352a
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Opus teacher head0.006
GPT teacher head0.277
- Teacher spread
- 0.271 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
The record
- Venue
- Nature Genetics
- Topic
- BRCA gene mutations in cancer
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- University of British ColumbiaPublic Health OntarioSimon Fraser UniversityMcGill UniversityUniversity Health NetworkHôpital du Saint-SacrementMcGill University and Génome Québec Innovation CentreQueen's UniversityLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalCentre Hospitalier de l’Université de MontréalUniversité LavalBC Cancer AgencyRoyal Victoria HospitalCentre hospitalier universitaire de QuébecUniversity of Toronto
- Funders
- Medical Research and Materiel CommandNational Institute of General Medical SciencesNational Human Genome Research InstituteNational Institute of Mental HealthErasmus Universitair Medisch Centrum RotterdamInstituto de Salud Carlos IIISydney Medical SchoolCancer Council Western AustraliaCancer Council NSWCancer Council VictoriaWorld Cancer Research FundEuropean Social FundMedical Research CouncilCancer Center, University of KansasNational Institutes of HealthCentre Léon BérardHellenic Health FoundationFreistaat SachsenAkershus UniversitetssykehusLiga Portuguesa Contra o CancroMutuelle Générale de l'Education NationaleInstitut Gustave-RoussyMinistero dello Sviluppo EconomicoAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du TravailHospices Civils de LyonCancer Council South AustraliaIstituto Oncologico VenetoInstituto MilleniumInstitut National Du CancerRadboud Universitair Medisch CentrumOulun YliopistoNational Health and Medical Research CouncilDeutsche KrebshilfeUniversitair Medisch Centrum GroningenLeids Universitair Medisch CentrumUniversitetet i BergenKarolinska InstitutetAssociazione Italiana per la Ricerca sul CancroFondation de FranceStavros Niarchos FoundationFisher Center for Alzheimer's Research FoundationPeter MacCallum Cancer CentreKuopion Yliopistollinen SairaalaBreast Cancer CampaignMinisterstvo Zdravotnictví Ceské RepublikyServicio Gallego de SaludInstitut BergoniéGreat Ormond Street Hospital for ChildrenFonds Wetenschappelijk OnderzoekMinisterio de Economía y CompetitividadErasmus Medisch CentrumDeutsche Gesetzliche UnfallversicherungNederlandse Organisatie voor Wetenschappelijk OnderzoekKing's College LondonGentofte HospitalCancerfondenCancer AustraliaRadboud UniversiteitRussian Foundation for Basic ResearchNorges ForskningsrådStockholms Läns LandstingUniversiteit MaastrichtVrije Universiteit AmsterdamUniversity of Western SydneyMaastricht Universitair Medisch CentrumNational Heart, Lung, and Blood InstituteOhio State UniversityUniversiteit LeidenUniversity of CreteMinistero della SaluteInstitut National de la Santé et de la Recherche MédicaleMedisinske fakultet, Universitetet i OsloHunter Medical Research InstituteDeutscher Akademischer AustauschdienstRobert Bosch StiftungIstituto Toscano TumoriTrinity College DublinAgency for Science, Technology and ResearchCenters for Disease Control and PreventionJewish General HospitalNational Institute for Health and Care ResearchUniversity of QueenslandHungarian Scientific Research FundCancer Association of South AfricaMedizinischen Hochschule HannoverCancer Institute NSWCanadian Institutes of Health ResearchLietuvos Mokslo TarybaEuropean CommissionDeutsches KrebsforschungszentrumUniversity of AberdeenQIMR Berghofer Medical Research InstituteFondation du cancer du sein du QuébecGénome QuébecUniversitetet i OsloUniversity of NottinghamCalvary Mater NewcastleNottingham University Hospitals NHS TrustNational Breast Cancer FoundationNational Institute of Environmental Health SciencesSwedish Cancer FoundationUniversité LavalRoyal Marsden NHS Foundation TrustLon V. Smith FoundationVlaamse regeringFundación Mutua MadrileñaHaukeland UniversitetssjukehusMinistère du Développement Économique, de l’Innovation et de l’ExportationUniversity of SouthamptonCancer Research UKAgence Nationale de la RechercheWellcome TrustDavid F. and Margaret T. Grohne Family FoundationBreast Cancer Research FoundationGeneralitat de CatalunyaUniverzita Karlova v PrazeKansas Bioscience AuthorityXunta de GaliciaIsrael Cancer AssociationDr. Ralph and Marian Falk Medical Research TrustUniversity Hospitals of Leicester NHS TrustNational Center for Advancing Translational SciencesFrancis Crick InstituteBundesministerium für Bildung und ForschungOvarian Cancer Research FundOdense UniversitetshospitalCentral Manchester University Hospitals NHS Foundation TrustNational Cancer InstituteEuropean Regional Development FundMinisterio de Sanidad, Servicios Sociales e IgualdadGovernment of CanadaNIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer ResearchNorges Teknisk-Naturvitenskapelige UniversitetCentre Hospitalier Universitaire de QuébecCancer Council TasmaniaItä-Suomen YliopistoGenome CanadaInstitut Català de la SalutNewcastle upon Tyne Hospitals NHS Foundation TrustCreighton UniversityInstitut Claudius RegaudCalifornia Department of Public HealthSundhed og Sygdom, Det Frie ForskningsrådUniversity of WashingtonMassachusetts Institute of TechnologyUniversity of TorontoUniversity of California, San FranciscoUniversitetet i TromsøSusan G. Komen for the Cure
- Keywords
- BiologyBreast cancerEstrogen receptorIdentification (biology)GeneticsEstrogenEstrogen receptor betaEstrogen receptor alphaOncologyInternal medicineCancerComputational biologyBioinformaticsMedicine
- Has abstract in OpenAlex
- no