Advantages of Post-Mastectomy Proton Beam Therapy in a Breast Cancer Patient With Pectus Excavatum
Bibliographic record
Abstract
Pectus excavatum (PE) is a chest wall deformity that can complicate the delivery of radiation therapy (RT) for breast cancer. This case report highlights the potential benefits of proton beam therapy (PBT) for these patients. We describe a case of a 79-year-old woman with PE who required post-mastectomy chest wall RT. Treatment plans were generated to deliver 45 Gy in 25 fractions with either PBT or conventional conformal photon RT. A 10-Gy boost to the post-mastectomy scar was used for both plans. A dosimetric benefit was observed for organs at risk with the PBT plan compared to the photon plan. PBT reduced mean doses to the lungs by more than 70% and to the heart by greater than 95%. The patient was treated with PBT with minimal acute toxicities. With the challenging chest anatomy of PE, PBT was selected as the treatment of choice for post-mastectomy radiation. The superior dosimetry can decrease the risks of post-treatment cardiac and pulmonary toxicities. J Med Cases. 2017;8(3):98-101 doi: https://doi.org/10.14740/jmc2781w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".