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Achievement of saturation targets in preterm infants <32 weeks’ gestational age in the delivery room

2017· article· en· W2596798571 on OpenAlexaff
Lani Nui White, Marta Thió, Louise Owen, C. Omar F. Kamlin, Samantha Sloss, Stuart B. Hooper, Peter G. Davis, Jennifer A. Dawson

Bibliographic record

VenueArchives of Disease in Childhood Fetal & Neonatal · 2017
Typearticle
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsRoyal Ottawa Mental Health Centre
FundersNational Health and Medical Research Council
KeywordsHyperoxiaFraction of inspired oxygenMedicineGestational ageAnesthesiaSupplemental oxygenGestationHypoxia (environmental)Oxygen saturationPulse oximetryHeart ratePediatricsBirth weightOxygenPregnancyLungInternal medicineBlood pressureChemistryMechanical ventilation

Abstract

fetched live from OpenAlex

Background To reduce the risks of hypoxia and hyperoxia in preterm infants in the delivery room; national and international guidelines recommend titrating supplemental oxygen delivery to achieve specific oxygen saturation (SpO 2 ) targets. Our aim was to measure the proportion of time infants <32 weeks' gestation spent within and outside prescribed SpO 2 targets during the first 10 min after birth. Method Prospective observational study using data from a preductal SpO 2 sensor and oxygen analyser measuring fraction of inspired oxygen (FiO 2 ) in the inspiratory limb of the respiratory circuit. Measurements of SpO 2 , heart rate and FiO 2 were recorded every 2 s. We assessed compliance with the upper SpO 2 limit only when infants were receiving supplemental oxygen. SpO 2 measurements were recorded as being below, within or above the target at each time point. We measured the number of times infants were continuously below or above the target range for more than 30 s. Results Twenty-seven infants; mean (SD) 28 (3.4) weeks and 962 (370) g were studied. Infants were below, within and above the prescribed targets for 28%, 35% and 37% of the first 10 min after birth, respectively. Conclusions Preterm infants spent almost two-thirds of the first 10 min after birth with oxygen saturations outside prescribed target ranges. New titration strategies are required to reduce the risks of hypoxia and hyperoxia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.256
Threshold uncertainty score0.720

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.318
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations34
Published2017
Admission routes1
Has abstractyes

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