EFFECTS OF DIFFERENT TYPES OF ANESTHESIA ON CEREBRAL OXYGENATION AND COGNITIVE FUNCTIONS IN CAROTID ENDARTERECTOMY
Bibliographic record
Abstract
Carotid endarterectomy (CEA) can be followed by postoperative cognitive dysfunction (POCD). Goal of the study: to investigate the effect of total intravenous anesthesia (TIVA) with propofol and inhalation anesthesia (IA) with sevoflurane on cerebral oxygenation and POCD. Materials and methods. 40 patients were enrolled into the study and divided into the groups of TIVA and IA. The cerebral tissue oxygen saturation with oxygen (SctO2) was recorded during CEA and in 24 hours after it. Cognitive functions were assessed with Montreal Cognitive Assessment (MoCA) before the CEA, in 1 and 5 days after. Results. Reduction of SctO 2 was observed on the operated side after carotid clamping. SctO 2 transitory reduced on the contralateral side in the TIVA group and was significantly higher in the IA group. MoCA changes in 24 hours after the surgery correlated with SctO 2 reduction on the ipsilateral side in TIVA group (rho = 0.54; p = 0.015). In 5 days after CEA, the cognitive functions were higher in the IA group (p = 0.028). Conclusion. Anesthesia with sevoflurane used for CEA may mitigate an asymmetry of cerebral perfusion, improves oxygenation of contralateral hemisphere and reduces the risk of POCD.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".