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Record W2600804207 · doi:10.1056/jw201009210000001

Milnacipran for Fibromyalgia

2010· article· en· W2600804207 on OpenAlexaboutno aff
Allan S. Brett

Bibliographic record

VenueJournal watch · 2010
Typearticle
Languageen
FieldMedicine
TopicFibromyalgia and Chronic Fatigue Syndrome Research
Canadian institutionsnot available
Fundersnot available
KeywordsMilnacipranFibromyalgiaMedicinePlaceboDosingRandomized controlled trialReuptake inhibitorAnesthesiaAntidepressantPsychiatryInternal medicineAlternative medicineAnxiety

Abstract

fetched live from OpenAlex

In January 2009, the FDA approved milnacipran (Savella), a selective serotonin and norepinephrine reuptake inhibitor, for treatment of fibromyalgia. In an industry-sponsored randomized trial, 1025 U.S. and Canadian patients with fibromyalgia (mean duration of symptoms, 11 years) received milnacipran or placebo. Dosing started at 12.5 mg once daily and was titrated to …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.328
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes1
Has abstractyes

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Same venueJournal watchSame topicFibromyalgia and Chronic Fatigue Syndrome ResearchFrench-language works237,207