SA121. Links Between Different Areas of Functioning, Social Anxiety, and Theory of Mind in Recent-Onset Schizophrenia
Bibliographic record
Abstract
Background: Functional recovery is now a recognized treatment goal for schizophrenia. It is therefore important to better understand the cognitive and psychological factors that influence functioning and their interrelations. Among these factors, social cognition deficits and comorbid social anxiety are common in schizophrenia and have been separately linked to greater impairments in functioning. In a previous study, we observed that theory of mind (ToM) was the aspect of social cognition that showed the greatest association with functioning in recent-onset schizophrenia. Contrary to our expectations, patients with or without social anxiety showed similar ToM performance and similar levels of functioning as assessed with the Social and Occupational Functioning Scale (SOFAS). Since the SOFAS provides a single, global score, we aimed to refine our previous results by exploring the relationships with distinct areas of functioning rated with the Schizophrenia Objective Functioning Instrument (SOFI). Methods: Fifty-six outpatients with recent-onset schizophrenia (mean illness duration = 21.2 months) had undergone a detailed interview that covered several aspects of their functioning. The records from these interviews were used to rate the 4 SOFI subscales, including (1) living situation, (2) instrumental activities of daily living, (3) productive activities and role functioning, and (4) social/recreational functioning. These ratings were compared between patients with (N = 27) or without (N = 29) a comorbid social anxiety disorder, and we also examined the link with ToM performance assessed with the Combined Stories Task. Results: No group difference emerged between patients with or without social anxiety on the 4 SOFI subscales (all Ps >. 30). As for the link with ToM, a significant correlation was observed with productive activities and role functioning (r = .31, P = .02). The other correlations did not reach significance (P values between .08 and .72). Conclusion: Previous studies reported poorer functioning in schizophrenia patients who also present with social anxiety, and the failure to replicate these results triggers questions regarding the factors at play. Here, we show that it was not our global measure of functioning that prevented us from observing an effect in our initial study. Another possibility is that differences in functioning are more specifically observed in more chronic patients or that some measures of functioning are more sensitive to the negative self-perception often linked with social anxiety. As for the link with ToM, the significant association only with productive activities and role functioning suggests that certain types of social interactions may be particularly affected by ToM deficits. We recently observed that ToM is linked to facilitation of social interactions when performing a collaborative task with another person, which could be particularly important in a work context.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".