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Record W2603149863 · doi:10.30699/mmlj17-01-03

Molecular Analysis of the Isolates of Acinetobacter baumannii isolated from Tehran Hospitals Using ERIC-PCR Method

2018· article· en· W2603149863 on OpenAlexvenueno aff
Abbas Maleki, J Vandyousefi, Zeinab Mirzaie, Sobhan Ghafourian, Hossein Kazemian, Noorkhoda Sadeghifard

Bibliographic record

VenueModern Medical Laboratory Journal · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAntibiotic Resistance in Bacteria
Canadian institutionsnot available
Fundersnot available
KeywordsAcinetobacter baumanniiMicrobiologyAcinetobacterBiologyAntibioticsGeneticsBacteriaPseudomonas aeruginosa

Abstract

fetched live from OpenAlex

infections, including pneumonia, bacteremia, surgical wound infections, urinary tract infections, and meningitis.In this study, enterobacterial repetitive intergenic consensus sequence-based PCR (ERIC-PCR) technique was used for analysis and molecular typing of Acinetobacter strains, which has high discrimination power compared to phenotypic markers. Methods:In the present study, a total of 40 A. baumanniies strains were isolated from patients hospitalized in Tehran hospitals.After identification and confirmation of the isolates by serotyping and biochemical tests, a single colony of each isolate was cultured on liquid LB medium, and after DNA extraction, PCR was performed.After electrophoresis of PCR product, gel images were stored electronically for analysis and comparison of the isolates. Results:In this study, 40 strains of A. baumannii were analyzed by ERIC-PCR method, of which 29 strains were typed into 10 groups and 11 other strains had no PCR bands or had a band that could not be assigned to any of the above groups.Conclusion: In this study, it was found that A. baumanniie strains could be typed using repetitive sequences.This extent of polymorphism shows that ERIC-PCR is a useful method for analysis of genetic variation of A. baumannii strains.High genetic variation of A. baumannii strains may be due to wide geographical distribution of this species in Iran

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.281
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2018
Admission routes1
Has abstractyes

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