Comment on the CTS 2015 guidelines for asthma in preschoolers
Bibliographic record
Abstract
The Canadian Thoracic Society (CTS) and the Canadian Paediatric Society (CPS) should be applauded for developing their position paper for ‘Diagnosis and Management of Asthma in Preschoolers’ (1,2). We would, however, like to draw attention to the term ‘frequent symptoms’, mentioned in this document for two domains—diagnosis and control of asthma and its relation to upper respiratory tract infection (URTI) episodes which are very common in preschoolers. Frequent symptoms in both domains of the CTS/CPS paper are defined as ‘at least 8 days a month of symptoms’. Unfortunately, no evidence supports that definition. Regarding the diagnosis domain, we would like to draw attention to the original GINA (Global Initiative for Asthma) approach (3). In this document, a probability-based approach is suggested, based on the pattern of symptoms during and between viral respiratory infections. Using this approach (Box 6-1 in GINA, see Figure 1), symptoms during an URTI that last <10 days, recurring less than four times a year and with no symptoms between episodes, are considered low probability of asthma (even in the presence of a positive response to ‘asthma’ treatment).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.021 | 0.099 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.005 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.004 | 0.006 |
| Scholarly communication | 0.004 | 0.006 |
| Open science | 0.008 | 0.004 |
| Research integrity | 0.048 | 0.060 |
| Insufficient payload (model declined to judge) | 0.011 | 0.008 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".