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Record W2608406261 · doi:10.1016/j.devcel.2017.02.006

Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

2017· article· en· W2608406261 on OpenAlex
Nicole A. J. Krentz, Dennis Van Hoof, Zhongmei Li, Akie Watanabe, Cuilan Nian, Michael S. German, Francis C. Lynn

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueDevelopmental Cell · 2017
Typearticle
Languageen
FieldMedicine
TopicPancreatic function and diabetes
Canadian institutionsBC Children's HospitalUniversity of British Columbia
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesNatural Sciences and Engineering Research Council of CanadaNational Institutes of HealthUniversity of British ColumbiaMichael Smith Health Research BCBC Children's HospitalNora Eccles Treadwell FoundationJuvenile Diabetes Research Foundation United States of AmericaCanadian Diabetes AssociationUniversity of CaliforniaAmerican Diabetes Association
KeywordsBiologyProgenitor cellCell cycleCell biologyProgenitorRestriction pointEnteroendocrine cellCyclin-dependent kinaseStem cellCellEndocrine systemEndocrinologyGeneticsHormone

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.283
Threshold uncertainty score0.336

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.238
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it