Bibliographic record
Abstract
Two stage exchange has been the gold standard in north America for the treatment of infected knee replacements. The choice of static versus articulated spacers has been debated for a number of years. At our institution our choice of spacer for 2 stage exchanges is an articulated spacer. This allows motion between stages which facilitates recovery, and makes the second stage technically easier. In a study from our institution we followed 115 infected TKAs treated with the PROSTALAC articulated spacer for 5–9 years. Success for eradication of infection was 88%. With a repeat two stage overall infection control was 98%. In addition we compared functional outcomes to a group of aseptic knee revisions and found no difference in functional outcomes with standard quality of life outcome scores. While the articulated spacers was our treatment of choice in 2 stage exchange around 2012 the company that manufactured the PROSTALAC knee components ceased to manufacture them. At that time based on the work of 2 previous studies (Hofmann, Lee), at our institution we continued to use articulated spacers. However, this was now the so called Hofmann technique with a new standard femoral component with an all polyethylene tibia. The only difference from a standard knee revision was no stems and the utilization of high dose antibiotics. We also followed the principles from Europe of one stage exchange, such as wide debridement and soaking in dilute betadine for 15 minutes. More recently as of Sept 2015 we have used an all-polyethylene tibia with a keel. The hope being that this will give a more stable tibia than previous and perhaps make a second stage unnecessary. Our first case was September 2015. The intention was not to do a second stage if the infection was eradicated and the patient had good pain relief and function. To date we have implanted 12 of these and in all cases we have not had to do a second stage revision. Further study will reveal where this inadvertent one stage fits in our practice.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.011 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.003 | 0.004 |
| Open science | 0.003 | 0.003 |
| Research integrity | 0.004 | 0.005 |
| Insufficient payload (model declined to judge) | 0.020 | 0.009 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".