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Record W2615996435 · doi:10.1111/voxs.12357

Survey for bacterial testing of platelet components in Latin America

2017· article· en· W2615996435 on OpenAlexafffund
Sandra Ramírez‐Arcos, Carl McDonald, Richard J. Benjamin

Bibliographic record

VenueISBT Science Series · 2017
Typearticle
Languageen
FieldMedicine
TopicAntiplatelet Therapy and Cardiovascular Diseases
Canadian institutionsCanadian Blood Services
FundersHealth CanadaCanadian Blood Services
KeywordsApheresisBuffy coatLatin AmericansContaminationQuarantineMedicinePlateletBiologySurgeryImmunologyPolitical sciencePathology

Abstract

fetched live from OpenAlex

Introduction Bacterial contamination of platelet concentrates ( PC s) poses the highest post‐transfusion infectious risk in developed countries. However, there is not extensive information about similar strategies implemented in Latin America. Aim To assess the status of platelet screening for bacterial contamination in Latin American blood banks. Methods An online‐based survey with 10 comprehensive questions was sent to 46 blood banks in five countries: Argentina, Brazil, Colombia, Honduras and Mexico. The centres were asked about PC production and shelf life, and strategies to improve PC safety. Centres were also surveyed regarding postsampling quarantine, results interpretation and haemovigilance data. Results Ten centres(21·8%) in four countries answered the survey. Annual PC production ranges from 600 to 19 200. All sites store PC s for 5 days, and eight sites use leucocyte reduction. Five centres(50%) produce apheresis and platelet‐rich‐plasma PC s, one centre(10%) produces buffy coat ( BC ) PC s, one centre(10%) produces apheresis PC s, and three centres(30%) produce apheresis and BC PC s. Nine sites reported using established donor skin donor disinfection protocols, eight employ first aliquot diversion, and two visually inspect PC s. Eight sites screen PC s for bacterial contamination with culture methods: three sites(37·5%) test 1% of outdated PC s and five sites(62·5%) test 100% of PC s 20‐24 h after blood collection. Of these five sites, two quarantine PC s for 24 h after sampling. Three sites have haemovigilance data, which are unavailable to the public. No sites have implemented pathogen reduction technologies. Conclusions Screening practices and mitigation strategies vary considerably between sites highlighting the need for standardisation of procedures in Latin America.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.263
Threshold uncertainty score0.403

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.314
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2017
Admission routes2
Has abstractyes

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