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Record W2616187926 · doi:10.1136/oem.2006.027631

Asbestos, smoking, and lung cancer: interaction and attribution

2006· letter· en· W2616187926 on OpenAlexaff
Bruce W. Case

Bibliographic record

VenueOccupational and Environmental Medicine · 2006
Typeletter
Languageen
FieldMedicine
TopicOccupational and environmental lung diseases
Canadian institutionsMcGill University Health CentreMcGill UniversityMontreal General Hospital
Fundersnot available
KeywordsMesotheliomaLung cancerAsbestosMedicineDiseaseCancerOncologyInternal medicinePathology

Abstract

fetched live from OpenAlex

Commentary on the paper by Reid et al (see page 509) Lung cancer is almost as dramatic a disease as is mesothelioma in its clinical course and prognosis. It has been a “rule of thumb” that there may be two asbestos related lung cancers for every mesothelioma, with a ratio of up to 10:1 in some heavily exposed occupational cohorts. Even in the United Kingdom, where mesothelioma deaths have risen so high they may have surpassed asbestos related lung cancer deaths,1 the latter remains estimated at 2–3% of all lung cancer. Due to disease time course, the potential effects of smoking cessation, and possibly improved screening of at-risk populations, lung cancer seems more amenable to early detection or prevention. Yet lung cancer receives far less attention, both scientifically and in the popular press. The problem is partly one of ease of attribution. For compensation boards and others charged with this task, this has proved more difficult for lung cancer. For mesothelioma, most—80% generally, and perhaps over 90% in the UK—are currently due to one factor. The potent associated influences of asbestos fibre type and of time from first exposure make deconstruction of the cause of individual cases of mesothelioma a straightforward matter given adequate information.2 Lung cancer has always presented less simple dilemmas. Approximately the same proportion of …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.101
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.275
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2006
Admission routes1
Has abstractyes

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