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Record W2620656784 · doi:10.4172/1488-5069.1000049

Vardenafil: The clinical trial experience

2003· article· en· W2620656784 on OpenAlexaffvenue
Peter Pommerville

Bibliographic record

VenueJournal of Sexual & Reproductive Medicine · 2003
Typearticle
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsUniversity of Victoria
Fundersnot available
KeywordsVardenafilMedicineClinical trialPharmacologyPsychologyErectile dysfunctionInternal medicineTadalafil

Abstract

fetched live from OpenAlex

Vardenafil is a new phosphodiesterase 5 inhibitor designed specifically to be an effective and safe oral treatment for erectile dysfunction (ED).The present review provides a broad overview, with emphasis placed on results from key studies that will impact patient and physician choice of an appropriate treatment for ED.In addition to being highly selective for phosphodiesterase 5, vardenafil shows strong efficacy in the broad range of ED patients, regardless of age, etiology or severity, or concomitant disorders (eg, diabetes).This, combined with a good cardiovascular safety profile and the added features of minimal interactions with food and alcohol, indicates that vardenafil is very likely to play an important role in the overall management of ED.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.009
Threshold uncertainty score0.048

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.010
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.225
GPT teacher head0.457
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes2
Has abstractyes

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