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Record W2620656784 · doi:10.4172/1488-5069.1000049

Vardenafil: The clinical trial experience

2003· article· en· W2620656784 on OpenAlex
Peter Pommerville

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
venuePublished in a venue whose home country is Canada.

Bibliographic record

VenueJournal of Sexual & Reproductive Medicine · 2003
Typearticle
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsUniversity of Victoria
Fundersnot available
KeywordsVardenafilMedicineClinical trialPharmacologyPsychologyErectile dysfunctionInternal medicineTadalafil

Abstract

fetched live from OpenAlex

Vardenafil is a new phosphodiesterase 5 inhibitor designed specifically to be an effective and safe oral treatment for erectile dysfunction (ED). The present review provides a broad overview, with emphasis placed on results from key studies that will impact patient and physician choice of an appropriate treatment for ED. In addition to being highly selective for phosphodiesterase 5, vardenafil shows strong efficacy in the broad range of ED patients, regardless of age, etiology or severity, or concomitant disorders (eg, diabetes). This, combined with a good cardiovascular safety profile and the added features of minimal interactions with food and alcohol, indicates that vardenafil is very likely to play an important role in the overall management of ED.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.196
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.225
GPT teacher head0.457
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it