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Development of Consensus Recommendations for Genomic Testing of Plasma Cell Neoplasms for Diagnosis and Prognosis

2017· article· en· W2624034585 on OpenAlexaff
Trevor J. Pugh, J. Lynn Fink, Xinyan Lu, Susan Matthew, Joyce Murata‐Collins, Urvashi Surti, Pascale Willem, Min Fang

Bibliographic record

VenueCancer Genetics · 2017
Typearticle
Languageen
FieldMedicine
TopicMultiple Myeloma Research and Treatments
Canadian institutionsPrincess Margaret Cancer CentreUniversity Health Network
Fundersnot available
KeywordsKRASMultiple myelomaPlasma cell neoplasmPlasma cellNeuroblastoma RAS viral oncogene homologBiologyPlasma cell leukemiaComputational biologyGeneticsBioinformaticsCancer researchOncologyMedicineMutationGeneImmunologyPlasmacytoma

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.131
metaresearch head score (Gemma)0.271
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.131
Threshold uncertainty score0.691

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1310.271
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0060.009
Bibliometrics0.0130.006
Science and technology studies0.0050.005
Scholarly communication0.0090.007
Open science0.0170.010
Research integrity0.0260.029
Insufficient payload (model declined to judge)0.0080.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.171
GPT teacher head0.387
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractno

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