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A case of hypocholesterolemia and steatosis in a carrier of a PCSK9 loss-of-function mutation and polymorphisms predisposing to nonalcoholic fatty liver disease

2017· article· en· 11 citations· W2624801309 on OpenAlex· 10.1016/j.jacl.2017.06.005

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Clinical case report of a PCSK9 mutation carrier.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

This reports a clinical case involving a genetic mutation and liver disease, not research itself.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: medium

Clinical genetics case of PCSK9 mutation and steatosis; title-domain clear despite empty abstract.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Journal of clinical lipidology
Topic
Lipoproteins and Cardiovascular Health
Field
Medicine
Canadian institutions
Université de MontréalMontreal Clinical Research Institute
Funders
Keywords
MedicineSteatosisHypocholesterolemiaNonalcoholic fatty liver diseaseFatty liverInternal medicineLoss functionDiseaseMutationGastroenterologyGeneticsGeneCholesterolPhenotypeBiology
Has abstract in OpenAlex
no